The hydrophobicity profiles of V-type proton ATPase subunit S1 variants from four different species allow one to immediately see the similarity and differences in those sequences. Areas with no divergence in the plot are conserved in terms of their hydrophobicity levels, while areas showing fluctuations are more divergent. To investigate the profiles more closely, try disabling select sequences using the eye symbol in the interface below. This way the most divergent variants can easily be identified. Using a larger smoothing window enables an easier identification of divergent areas, while a smaller window points towards specific residues.
If you need to investigate closer zoom into the graph using the scrollwheel of you mouse, shift the plot by click and dragging it or hover over a line to see it's sequence name.
Note: not all options are available in all the examples - each is intended to highlight a specific part of the tool.
Data: Uniprot IDs Q15904 (human), O54715 (mouse), Q9R1Q9 (rat), P40682 (bovine)
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